无需家属陪护医院 淄博市骨科专科医院 淄博市医保定点医院

股骨头坏死治疗现状

2022-09-16
莲池小骨
阅读次数:0

股骨头无菌性坏死的保守治疗方法,主要是由Ficat等前人推荐的股骨颈髓芯减压。由于其治疗结果不一致,后又优化为带血管游离腓骨移植,或往股骨头坏死区注射自体干细胞。法国的倡导者发表了长期治疗结果,显示在股骨头坏死早期治疗有效,而且股骨头仍保持圆形。

但近十年来,在没有倡导者的报告中,在对照研究中、有时在随机研究中,对单纯髓芯减压提出了反对意见。确认了在坏死区域再生、和稳定的可能性。但这些技术不易运用。细胞治疗技术需要对骨髓组织进行离心、得到富集血液细胞的小球。已经证明该技术长期有效性和安全性,应用于年轻的、影像正常、MRI诊断股骨头坏死的患者。但很多股骨头软骨分离、股骨头塌陷的患者,除了全髋关节置换,没有更好的选择。

人工关节置换技术可靠,应用氧化铝陶瓷,随访20年以上,未发现磨损和骨溶解。虽然对这些年轻和活动量大的患者,存在关节不稳、假体周围骨折等并发症。

图片

图1 该患者39岁,花园体力劳动者,因双髋疼痛求诊,发现双侧股骨头坏死、左股骨头塌陷。左侧进行全髋关节置换,无症状的右髋注射了干细胞。术后1年X线片显示,右股骨头保持圆形。

图片

图2 同一患者术后一年双髋核磁,无并发症

图片

图3 术后三年,右侧股骨头轻度塌陷

图片

图4 同一患者术后3年,核磁显示右股骨头坏死软骨分离。患者尚未回归工作,坐姿活动无疼痛;跑步或某天剧烈运动后感受到右腹股沟中度疼痛。他对置换一侧的结果很满意,想急于做右侧手术,以便早日恢复职业工作。


原文导读

Treatments ofavascular osteonecrosis of the hip:Current treatments

Conservativetreatments for aseptic osteonecrosis of the femoral head have their ancestor inthe core decompression of the femoral neck, recommended by Ficat. Due toinconsistent results, this treatment has been optimized by either vascularizedfibular grafting, or by injecting autologous stem cells into the necrotic zone.The French promoters have published long-term results, showing efficacy in theearly stages of the disease, where the femoral head has not yet lost itssphericity. Over the last 10years, comparative studies, sometimes randomized,opposing them to simple core decompression, have been published bynon-promoters, confirming the possibility of stabilization or even regressionof necrosis area. But these techniques are not easy to implement. Cell therapyrequires treatment of marrow samples by centrifugation to obtain a pellet witha high concentration of haematopoietic cells. The now proven long-term efficacyas well as the safety of this technique make it the method of choice fortreating young patients detected at the sub-radiological stage by MRI.Unfortunately, many are seen late with detached cephalic cartilage or collapsedfemoral head and have no other option than total hip arthroplasty. Thistechnique is very reliable. With alumina ceramics, results of more than 20yearsshow the absence of wear and osteolysis, although other complications such asinstability or periprosthetic fractures may occur in these young and activepatients.

文献出处:Massin P.Treatments of avascular osteonecrosis of the hip: Current treatments. Morphologie. 2021 Jun; 105(349): 120-126. doi: 10.1016/j.morpho.2020.06.003. Epub2020 Jul 8. PMID: 32653168.

↑向上滑动阅读全文↑

来源:304关节学术

译者:罗殿中

扫一扫

官方客服微信加为好友